research grade cm5 sensor chips (Biacore)
86
Structured Review
Biacore
research grade cm5 sensor chips
Research Grade Cm5 Sensor Chips, supplied by Biacore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cm5+research+grade+sensor+chips/chip+cm5+sensor/pmc12780224-353-18-22
Average 86 stars, based on 1 article reviews
Research Grade Cm5 Sensor Chips, supplied by Biacore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cm5+research+grade+sensor+chips/chip+cm5+sensor/pmc12780224-353-18-22
Average 86 stars, based on 1 article reviews
research grade cm5 sensor chips - by Bioz Stars,
2026-09
86/100 stars
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other:Article Title: Domain 5 of the cation-independent mannose 6-phosphate receptor preferentially binds phosphodiesters (mannose 6-phosphate N-acetylglucosamine ester). Article Snippet: The 300 kDa cation-independent mannose 6-phosphate receptor (CI-MPR) and the 46 kDa cation-dependent MPR (CD-MPR) are key components of the lysosomal enzyme targeting system that bind newly synthesized mannose 6-phosphate (Man-6-P)-containing acid hydrolases and divert them from the secretory pathway.. Previous studies have mapped two high-affinity Man-6-P binding sites of the CIMPR to domains 1-3 and 9 and one low-affinity site to domain 5 within its 15-domain extracytoplasmic region.. A structure-based sequence alignment predicts that domain 5 contains the four conserved residues (Gln, Arg, Glu, Tyr) identified as essential for Man-6-P binding by the CD-MPR and domains 1-3 and 9 of the CI-MPR. Article Title: Inhibitory action of polyunsaturated fatty acids on Cdt1-geminin interaction Article Snippet: Article Title: Phosphotetrahydropyran compounds for the treatment of wounds and fibrotic disorders Article Snippet: CM5 research grade sensor chips, surfactant P20 and Article Title: Molecular tools for metalloprotease sub-proteome generation. Article Snippet: Molecular systems biology, the highly challenging post-genomic research area has many different facets like transcriptomics, roteomics, metabolomics, interactomics, modelling of cell cycles, etc.. Among them, functional proteomics and interactomics epresent exciting fields of research with high relevance towards biochemistry, medicinal chemistry, therapy, biotechnology and ioinformatics.. The number of different proteins expressed by a cell under a set of certain conditions and the high dynamic range f these proteins together with different activation states require methods for sub-proteome generation on a mechanistic basis to educe the amount of data. Article Title: Minichaperone (GroEL191-345) mediated folding of MalZ proceeds by binding and release of native and functional intermediates. Article Snippet: CM5 research grade sensor chips and Article Title: Coenzyme Q10 as a potent compound that inhibits Cdt1-geminin interaction. Article Snippet: A human replication initiation protein Cdt1 is a very central player in the cell cycle regulation of DNA replication, and geminin down-regulates Cdt1 function by directly binding to it.. It has been demonstrated that Cdt1 hyperfunction resulting from Cdt1–geminin imbalance, for example by geminin silencing with siRNA, induces DNA re-replication and eventual cell death in some cancer-derived cell lines.. In the present study, we first established a high throughput screening system based on modified ELISA (enzyme linked immunosorbent assay) to identify compounds that interfere with human Cdt1–geminin binding. Article Title: The inhibitory action of long-chain fatty acids on the DNA binding activity of p53. Article Snippet: The in vitro relationship between human p53 DNA binding domain (p53 DBD) and FA was investigated.. We found that saturated and monounsaturated long-chain FA inhibited the double-stranded DNA (dsDNA) binding activity of p53 DBD.. The strongest inhibitors of saturated and unsaturated FA were docosanoic acid (22:0) and cis-12-heneicosenoic acid (21:1n-9), respectively. n-Octadecane, trans-unsaturated FA, and FAME had no influence on the binding activity of p53 DBD, showing that the FA structures such as one or no double bond of cis configuration, hydrocarbon chain of length C20 to C22, and free carboxyl groups are important for the inhibition. Article Title: Cholesterol hemisuccinate: a selective inhibitor of family X DNA polymerases. Article Snippet: Cholesterol hemisuccinate (compound 5), which consists of succinic acid esterified to the b-hydroxyl group of cholesterol, selectively and strongly inhibited the activities of mammalian DNA polymerases (pols) such as pol b, pol k, and terminal deoxynucleotidyltransferase (TdT), which are family X pols, in vitro, and the IC50 values were 2.9, 6.3, and 6.5 lM, respectively.. The compound moderately suppressed the activities of other mammalian pols such as pol A (i.e., pol c), pol B (i.e., pols a, d, and e), and pol Y (i.e., pols i, g, and j) with 50% inhibition observed at concentrations of 131, 89.2–98.0, and 120–125 lM, respectively.. The compound had no influence on the activities of plant pols a and b, prokaryotic pols and other DNA metabolic enzymes tested. |